Sample Matrix Selection Guide « Center for Applied Isotope Studies (CAIS)

Solution-based ICP analyses require complete dissolution of the sample. Different chemical methods may need to be utilized to dissolve a sample completely. For instance, nitric acid is widely used as a digesting agent and a solvent in ICP analyses because of its oxidizing capabilities and the solubility of nitrate salts. However, platinum group metals require the addition of hydrochloric acid to promote dissolution.

The following tables provide solubility information for various elements in different matrices. Periodic table titled DI Water Matrices, used in the Plasma Chemistry Laboratory, with certain elements highlighted in green to indicate water solubility. A note explains the relevance of DI water and the highlighted elements. Periodic table for laboratory use, highlighting elements stable (purple) or dissolvable (green) in nitric acid; non-highlighted ones play minimal roles in plasma chemistry or nitric acid reactions. Periodic table highlighting elements stable or soluble in aqueous HCl in orange—hydrogen, carbon, nitrogen, oxygen, and noble gases are not highlighted; ideal for Plasma Chemistry Laboratory reference.